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Breast cancer (BC) is the commonest human cancer and its incidence (BC incidence, BCI) is rising worldwide. Whilst both tobacco and alcohol have been linked to BCI genotoxic cannabinoids have not been investigated…Data show that exposure to cannabis and the cannabinoids Δ9-tetrahydrocannabinol, (THC) CBD, CBG and alcoholism fulfil quantitative causal criteria for BCI across space and time. Findings are robust to adjustment for age and several known sociodemographic, socio-economic and hormonal risk factors and establish cannabinoids as an additional risk factor class for breast carcinogenesis. BCI is higher under cannabis-liberal legal paradigms.
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(Europe is not exempt from cannabis caused congenital cannabis defects)
Data indicate that metrics of cannabis exposure are closely linked with CLAR and satisfy epidemiological criteria for causality. Along with Hawaii and the USA, Europe now forms the third international population in which this causal link has been demonstrated. Cannabis as a predictor of limb anomalies was more potent than tobacco or alcohol. Cannabinoid access should be restricted to protect public health and the community genome/epigenome transgenerationally.
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Compared with non-users, female athletes who regularly use cannabis had reduced early anaerobic power production and may have an increased risk for cardiovascular disease, according to published results.
Researchers from the School of Sport and Exercise Science at the University of Northern Colorado…overall, found non-users produced “significantly greater” anaerobic power output compared with cannabis users, as determined by stage-1 and stage-2 Wingate assessment scores. However, researchers noted anaerobic fatigue, as determined by 30-second Wingate assessment scores, was “significantly lower” in cannabis users (51%) compared with non-users (61%).
Despite comparable body composition and cardiovascular fitness between the cohorts, average C-reactive protein concentration levels determined cannabis user had an increased risk for cardiovascular disease (CVD) compared with non-users.
“Chronic use of cannabis in physically active female athletes may be linked to lower initial power output and higher risk for CVD as defined by CRP,” the researchers wrote in the study. “This study is important in that it provides a glimpse into where cannabis may begin to influence the health and athletic performance in young adults,” they concluded.
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Research on pot and sperm quality, gene expression, and child development.
July 28, 2022
KEY POINTS
- Paternal consumption of marijuana prior to conception has been found in rodent studies to alter offspring brain development.
- Children whose fathers consumed marijuana during their partner's pregnancy may be at higher risk of psychotic symptoms.
- Pot consumption can trigger epigenetic changes in gene expression, which fathers can pass along to their children.
- Not all human studies of pot's effects on male fertility are consistent. A dose-dependent relationship between pot and male fertility may exist.
Accumulating evidence suggests that a man’s lifetime cannabis consumption can influence his fertility as well as the health and development of his future children. While occasional use may not have terrible consequences, prospective fathers (and their partners) should be mindful of how marijuana use, especially in the months leading up to conception, can affect sperm—and the expression of genes those sperm pass on to offspring.
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This disturbing evidence has significant ramifications for #publichealth for the entire community. Cannabis as a predictor of limb anomalies was more potent than tobacco or alcohol. Cannabinoid access should be restricted to protect public health and the community genome/epigenome transgenerationally.
- High-strength cannabis linked to addiction and mental health problems
- Careful with CBD – Very Careful: Some CBD Creams, Patches Don't Match Labels: Study
- European Epidemiological Patterns of Cannabis- and Substance-Related Body Wall Congenital Anomalies: Geospatiotemporal and Causal Inferential Study
- Marijuana users more likely to need emergency care and hospitalization, study finds