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Key Points
- Driving under the influence of cannabis has been identified as a public health concern as medical and recreational cannabis availability increases in some countries.
- A recent randomized clinical trial found similar levels of acute driving impairment with THC-dominant cannabis and with a combination of THC-CBD equivalent cannabis using on-road driving tests that provided real-world conditions; however, CBD-dominant cannabis did not produce significant cognitive or psychomotor impairment compared with placebo in this trial.
- Media coverage of this study conveyed the findings as CBD-dominant cannabis not causing driving impairment while THC-dominant cannabis does, with the latter lasting up to 4 h post-dose.
- It is recommended that clinicians counsel about the risks of driving impairment when patients disclose use of cannabis products containing THC.
Also See
Cannabis use altering key functions like three-dimensional vision
“Medicinal” Cannabis & Driving – is it an Issue?
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by Society for the Study of Addiction
A systematic review published today in the scientific journal Addiction has found that cannabis use leads to acute cognitive impairments that may continue beyond the period of intoxication. This Canadian-led meta-review (review of reviews) merged the findings of 10 meta-analyses representing more than 43,000 participants.
The study found that cannabis intoxication leads to small to moderate cognitive impairments in areas including
- making decisions,
- suppressing inappropriate responses,
- learning through reading and listening,
- the ability to remember what one reads or hears, and
- the time needed to complete a mental task.
These and other acute impairments mirror the residual effects documented for cannabis use, suggesting that the damaging effects of cannabis begin while it is being consumed and persist beyond that period.
For complete Research (medicalxpress.com) and Dellazizzo - 2022 - Addiction - Wiley Online Library
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Exposure to Pro and Anti-Cannabis Social Media Messages and Teens’ and College Students’ Intentions to Use Cannabis
Content analyses have documented that posts about cannabis are increasingly common on social media. The relationship between the cannabis-related content to which teens and college students are exposed on social media and how such content may be associated with intentions to use and use of cannabis is less known, however. We conducted an online survey with teens (N = 350) who lived in Washington state using online survey panel participants in June 2018 and with college students (N = 966) in a Washington state-wide university system in February and March 2019. Participants in both samples reported seeing both pro-cannabis and anti-cannabis messages on social media platforms.
- Exposure to pro-cannabis messages on social media was associated with an increased intention to use cannabis.
- Exposure to anti-cannabis messages on social media was indirectly associated with decreased intentions to use cannabis through negative outcome beliefs of cannabis use and, among college students, through perceived norms.
- Among college students specifically, exposure to pro-cannabis messages on social media was also associated with more frequent cannabis use.
- Health communicators could focus anti-cannabis messaging on negative outcome beliefs among teens and college students as well as norms among college students to potentially influence constructs associated with intentions and use.
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JAMA Health Forum. 2023;4(1):e225041. doi:10.1001/jamahealthforum.2022.5041
Key Points
Question What is the association between legalization of recreational cannabis edibles and unintentional pediatric cannabis poisoning?
Findings This cross-sectional study of all children (n = 3.4 million) aged 0 to 9 years across 4 Canadian provinces found that jurisdictions that allowed the sale of cannabis edibles experienced much larger increases in cannabis poisonings and proportions of overall poisoning hospitalizations due to cannabis than the jurisdiction that prohibited edibles.
Meaning These findings suggest that restricting the sale of legal cannabis edibles may be a key policy to prevent unintentional pediatric cannabis poisonings following legalization.
Abstract
Objective To evaluate changes in proportions of all-cause hospitalizations for poisoning due to cannabis in children during 3 legalization policy periods in Canada’s 4 most populous provinces (including 3.4 million children aged 0-9 years).
Exposures Prelegalization (January 2015 to September 2018); period 1, in which dried flower only was legalized in all provinces (October 2018 to December 2019); and period 2, in which edibles were legalized in 3 provinces (exposed provinces) and restricted in 1 province (control province) (January 2020 to September 2021).
Main Outcomes and Measures The primary outcome was the proportion of hospitalizations due to cannabis poisoning out of all-cause poisoning hospitalizations. Data analysis was performed using descriptive statistics and Poisson regression models.
Results During the 7-year study period, there were 581 pediatric hospitalizations for cannabis poisoning (313 [53.9%] boys; 268 [46.1%] girls; mean [SD] age, 3.6 [2.5] years) and 4406 hospitalizations for all-cause poisonings. Of all-cause poisoning hospitalizations, the rate per 1000 due to cannabis poisoning before legalization was 57.42 in the exposed provinces and 38.50 in the control province. During period 1, the rate per 1000 poisoning hospitalizations increased to 149.71 in the exposed provinces (incidence rate ratio [IRR], 2.55; 95% CI, 1.88-3.46) and to 117.52 in the control province (IRR, 3.05; 95% CI, 1.82-5.11). During period 2, the rate per 1000 poisoning hospitalizations due to cannabis more than doubled to 318.04 in the exposed provinces (IRR, 2.16; 95% CI, 1.68-2.80) but remained similar at 137.93 in the control province (IRR, 1.18; 95% CI, 0.71-1.97).
Conclusions and Relevance This cross-sectional study found that following cannabis legalization, provinces that permitted edible cannabis sales experienced much larger increases in hospitalizations for unintentional pediatric poisonings than the province that prohibited cannabis edibles. In provinces with legal edibles, approximately one-third of pediatric hospitalizations for poisonings were due to cannabis. These findings suggest that restricting the sale of legal commercial edibles may be key to preventing pediatric poisonings after recreational cannabis legalization
Source: JAMA Health Forum – Health Policy, Health Care Reform, Health Affairs | JAMA Health Forum
- Long-Term Outcomes of Adolescent THC Exposure on Translational Cognitive Measures in Adulthood in an Animal Model and Computational Assessment of Human Data
- Smoke and minors: Child marijuana use has soared 250% in last 20 years — replacing alcohol as the drug of choice for under-18s
- Research shows cannabis use in adolescents linked with anxiety and memory loss
- Cannabis & Hemp – A Scientific Review of the Evidence
